The objective of Co-Extra is to provide all the stakeholders of the food and feed chains with a central decision-support system integrating the tools, methods, models and guidelines needed to deal with the imminent arrival of large quantities of GMOs, further to the lift of the current de facto ban on GMOs in the EU. Co-Extra will study and validate biological containment methods and model supply chain organisations and provide practical tools and methods for implementing co-existence. In parallel, Co-Extra will design and integrate GMO detection tools, develop sampling plans, and elaborate new techniques to meet the challenges raised by stacked genes and as yet unapproved or unexamined GMOs. Co-Extra will also study and propose the most appropriate information structure, content and flow management for ensuring reliable and cost-effective documentary traceability. All of the methods and tools that will be studied and developed will be assessed not only from the technical point of view but also with regard to economic and legal aspects. In parallel, to promote harmonisation of co-existence and traceability practices around the world, Co-Extra will survey the GMO-related legal regimes and practices that exist in and beyond the EU. Stakeholders will be involved in the project from the start through the dialogue platform, editorial offices, focus groups, national relays, etc. Co-Extra outcomes will contribute to reinforcing consumers confidence in labelling claims and therefore EU products at large. By helping economic stakeholders to meet consumers requirements for reliable choices, Co-Extra will improve European competitiveness. Co-Extra outcomes will be proposed to standardisation after validation. Dissemination activities will largely benefit from the strong commitment of the European Network of GMO Laboratories.